United States securities and exchange commission logo

                           June 30, 2020

       Helen Sabzevari
       President and Chief Executive Officer
       Precigen, Inc.
       20374 Seneca Meadows Parkway
       Germantown, Maryland 20876

                                                        Re: Precigen, Inc.
Statement on Form S-3
                                                            Filed June 22, 2020
                                                            File No. 333-239366

       Dear Ms. Sabzevari:

              This is to advise you that we have not reviewed and will not
review your registration

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact Scott
Anderegg, Staff Attorney at 202-551-3342 with any questions.


                           Division of Corporation Finance

                           Office of Trade & Services