August 15, 2019

Rick Sterling
Chief Financial Officer
Intrexon Corporation
20374 Seneca Meadows Parkway
Germantown, MD 20876

       Re: Intrexon Corporation
           Form 10-K for the Fiscal Year Ended December 31, 2018
           Filed March 1, 2019
           Form 10-Q for the Quarter Ended June 30, 2019
           Filed August 9, 2019
           File No. 001-36042

Dear Mr. Sterling:

      We have reviewed your filings and have the following comment. In our
comment, we
may ask you to provide us with information so we may better understand your

       Please respond to this comment within ten business days by providing the
information or advise us as soon as possible when you will respond. If you do
not believe our
comment applies to your facts and circumstances, please tell us why in your

       After reviewing your response to the comment, we may have additional

Form 10-Q for the Quarter Ended June 30, 2019

Management's Discussion and Analysis of Financial Condition and Results of
Operations, page

1.    We note that as a result of the re-alignment of your business in April
2019, you now
      report multiple segments and include a discussion of your segment results
that is limited
      to changes in your Segment Adjusted EBITDA. Please expand your disclosure
to include
      a comparative discussion of the revenues generated by each of your
reportable segments,
      the results of the operations that have been aggregated in the All Other
segment and the
      unallocated corporate costs that are excluded from your segment results
or tell us why you
      believe these disclosures are not required to provide a comprehensive
analysis of your
      results of operations. Refer to Item 303(b) of Regulation S-K and SEC
Release No. 33-
 Rick Sterling
Intrexon Corporation
August 15, 2019
Page 2

        We remind you that the company and its management are responsible for
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments, action
or absence of
action by the staff.

       You may contact Steve Lo at 202-551-3394 or Craig Arakawa at
202-551-3650 with any

FirstName LastNameRick Sterling
                                                          Division of
Corporation Finance
Comapany NameIntrexon Corporation
                                                          Office of Beverages,
Apparel and
August 15, 2019 Page 2                                    Mining
FirstName LastName