0001356090-24-000017 | 10-Q | XBRL Viewer

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Condensed Consolidated Statements of Cash Flows (Parenthetical) $ in Thousands	6 Months Ended
	Jun. 30, 2023 USD ($)
Statement of Cash Flows [Abstract]
Payment for debt extinguishment or debt prepayment cost	$ 120

Income Taxes	6 Months Ended
Income Taxes	Jun. 30, 2024
Income Tax Disclosure [Abstract]
Income Taxes	Income Taxes For the three and six months ended June 30, 2024 and 2023, the Company calculated its tax benefit using the estimated annual effective tax rate method. The rate is the ratio of estimated annual income tax expense related to estimated pretax loss from continuing operations, excluding significant unusual or infrequently occurring items. As a result of the pretax losses anticipated for the full year which are not benefited, this rate has been calculated and applied to the year-to-date interim period’s ordinary income or loss on a jurisdiction by jurisdiction basis to determine the income tax expense/benefit allocated to the year-to-date period. The annual effective tax rate is revised, if necessary, at the end of each interim period based on the Company’s most current best estimate. The Company recorded an income tax benefit of $1,689 and $65 for the three months ended June 30, 2024 and 2023, respectively, and $1,718 and $120 for the six months ended June 30, 2024 and 2023, respectively. The effective tax rate differs from the U.S. statutory tax rate, primarily as a result of the change in valuation allowance required. The increase in tax benefit recognized in the three and six months ended June 30, 2024 is primarily caused by the non-cash impairment of ActoBio's developed technology and goodwill, which resulted in the reduction of the associated deferred tax liability, and was recorded as a discrete item in the period. The Company's net deferred tax assets are offset by a valuation allowance due to the Company's history of net losses combined with an inability to confirm recovery of the tax benefits of the Company's tax attributes and other net deferred tax assets. In assessing the realizability of deferred tax assets, management considers whether it is more likely than not that some portion or all of the deferred tax assets will not be realized. The ultimate realization of deferred tax assets is dependent upon the generation of future taxable income during the periods in which those temporary differences become deductible. Management considers the scheduled reversal of deferred tax liabilities, projected future taxable income and tax planning strategies in making this assessment.

- Definition

The entire disclosure for income tax.

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+ Details

Share-Based Payments - Schedule of Restricted Stock Unit Activity (Details) - Restricted stock units - $ / shares	6 Months Ended	12 Months Ended
	Jun. 30, 2024	Dec. 31, 2023
Number of Restricted Stock Units
Balances at beginning of period (in shares)	961,534
Granted (in shares)	4,464,724
Vested (in shares)	(4,639,549)
Forfeited (in shares)	0
Balances at end of period (in shares)	786,709	961,534
Weighted Average Grant Date Fair Value
Balances at beginning of period (in dollars per share)	$ 1.17
Granted (in dollars per share)	1.42
Vested (in dollars per share)	1.37
Forfeited (in dollars per share)	0
Balances at end of period (in dollars per share)	$ 1.43	$ 1.17
Additional Information
Weighted Average Remaining Contractual Term (Years)	7 months 13 days	2 months 8 days

Summary of Significant Accounting Policies - Net (Loss) Income Per Share - Additional Information (Details) - shares	6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Total	28,190,478	24,202,403
Options
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Total	27,403,769	22,325,095
Restricted stock units
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Total	786,709	1,877,308

Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Current assets
Cash and cash equivalents	$ 9,345	$ 7,578
Short-term investments	10,191	55,277
Receivables
Trade, less allowance for credit losses of $0 and $184 as of June 30, 2024 and December 31, 2023	511	902
Other	505	673
Prepaid expenses	3,163	4,325
Total current assets	23,715	68,755
Property, plant and equipment, net	13,451	7,111
Intangible assets, net	5,091	40,701
Goodwill	24,918	26,612
Right-of-use assets	5,550	7,097
Other assets	435	767
Total assets	73,160	151,043
Current liabilities
Accounts payable	4,846	1,726
Accrued compensation and benefits	6,675	8,250
Other accrued liabilities	6,642	6,223
Settlement and indemnification accruals	3,213	5,075
Deferred revenue	378	509
Current portion of lease liabilities	1,269	1,202
Total current liabilities	23,023	22,985
Deferred revenue, net of current portion	1,818	1,818
Lease liabilities, net of current portion	5,072	5,895
Deferred tax liabilities	77	1,847
Total liabilities	29,990	32,545
Commitments and contingencies (Note 13)
Shareholders' equity
Common stock, no par value, 400,000,000 shares authorized as of June 30, 2024 and December 31, 2023; 256,398,527 shares issued as of June 30, 2024 and December 31, 2023, $252,656,151 shares and $248,919,096 shares outstanding as of June 30, 2024 and December 31, 2023, respectively.	0	0
Additional paid-in capital	2,093,080	2,084,916
Accumulated deficit	(2,047,001)	(1,964,471)
Accumulated other comprehensive loss	(2,909)	(1,947)
Total shareholders' equity	43,170	118,498
Total liabilities and shareholders' equity	$ 73,160	$ 151,043

Operating Leases - Maturities of Lease Liabilities (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Lessee, Operating Lease, Liability, Payment, Due [Abstract]
2024	$ 1,090
2025	1,611
2026	1,473
2027	1,303
2028	1,260
2029	1,295
Thereafter	552
Total	8,584
Present value adjustment	(2,243)
Total	6,341
Current portion of lease liabilities	1,269	$ 1,202
Long-term portion of operating lease liabilities	$ 5,072	$ 5,895

Share-Based Payments

6 Months Ended

Jun. 30, 2024

Share-Based Payment Arrangement [Abstract]

Share-Based Payments

The Company measures the fair value of stock options and RSUs issued to employees and nonemployees as of the grant date for recognition of stock-based compensation expense. Stock-based compensation expense for employees and nonemployees is recognized over the requisite service period, which is typically the vesting period. Stock-based compensation costs included in the condensed consolidated statements of operations are presented below:


	Three Months Ended June 30,				Six Months Ended June 30,
	2024		2023		2024		2023
Cost of products and services	$	(5)	$	17	$	12	$	35

Research and development	920		582		1,454		1,087
Selling, general and administrative	1,049		1,589		3,079		4,198

Total	$	1,964	$	2,188	$	4,545	$	5,320

Precigen Equity Incentive Plans

In August 2013, Precigen adopted the 2013 Omnibus Incentive Plan ("the 2013 Plan"), for employees and nonemployees which provided for grants of share-based awards, including stock options, RSUs, shares of common stock and other awards, to employees, officers, consultants, advisors, and nonemployee directors. Upon the effectiveness of the 2023 Omnibus Incentive Plan in June 2023, as discussed in the next paragraph, (the "2023 Plan"), no new awards may be granted under the 2013 Plan and any awards granted under the 2013 Plan prior to the effectiveness of the 2023 Plan will remain outstanding under such plan and will continue to vest and/or become exercisable in accordance with their original terms and conditions. As of June 30, 2024, there were 17,633,646 stock options and no RSUs outstanding under the 2013 Plan.

In April 2023, Precigen adopted the 2023 Plan, which became effective upon shareholder approval in June 2023. The 2023 Plan permits the grant of share-based awards, including stock options, restricted stock awards, and RSUs and other awards, to officers, employees and nonemployees. The 2023 Plan authorizes for issuance pursuant to awards under the 2023 Plan an aggregate of 16,418,137 shares, which included shares remaining available for issuance under the 2013 Plan as of the adoption of the 2023 Plan. As of June 30, 2024, there were 6,004,500 stock options and no RSUs outstanding under the 2023 Plan and 8,042,752 shares were available for future grants. On May 28, 2024, Precigen's board of directors approved an increase of 2,000,000 shares of common stock to be reserved for issuance under the 2023 Plan, which was subsequently approved by its shareholders at Precigen's annual meeting on July 5, 2024.

In April 2019, Precigen adopted the 2019 Incentive Plan for Non-Employee Service Providers (the "2019 Plan"), which became effective upon shareholder approval in June 2019. The 2019 Plan permits the grant of share-based awards, including stock options, restricted stock awards, and RSUs, to nonemployee service providers, including board members. As of June 30, 2024, there were 12,000,000 shares authorized for issuance under the 2019 Plan, of which 3,765,623 stock options and 786,709 RSUs were outstanding and 2,739,963 shares were available for future grants.

Stock option activity was as follows:


	Number of Shares	Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (Years)
Balances at December 31, 2023	22,057,340	$	6.90	7.47
Granted	6,852,634	1.41

Exercised	(36,458)	1.42
Forfeited	(611,750)	1.51
Expired	(857,997)	16.23
Balances at June 30, 2024	27,403,769	5.36		7.47
Exercisable at June 30, 2024	15,595,522	8.17		6.20

RSU activity was as follows:


	Number of Restricted Stock Units	Weighted Average Grant Date Fair Value		Weighted Average Remaining Contractual Term (Years)
Balances at December 31, 2023	961,534	$	1.17	0.19
Granted	4,464,724	1.42
Vested	(4,639,549)	1.37
Forfeited	—	—
Balances at June 30, 2024	786,709	1.43		0.62

Precigen currently uses treasury shares and authorized and unissued shares to satisfy share award exercises.

Segments - Additional Information (Details)	3 Months Ended		6 Months Ended		12 Months Ended
Segments - Additional Information (Details)	Jun. 30, 2024 USD ($) customer	Jun. 30, 2023 USD ($) customer	Jun. 30, 2024 USD ($) customer	Jun. 30, 2023 USD ($) customer	Dec. 31, 2023 USD ($)
Non-US
Segment Reporting Information [Line Items]
Long-Lived Assets, Including Property, Plant, and Equipment and Right Of Use Assets	$ 0		$ 0		$ 1,958,000
Revenues			$ 0		$ 0
Exemplar
Segment Reporting Information [Line Items]
Percentage of revenue attributable to customer	74.80%	73.30%	65.50%	78.00%
Number of customers \| customer	4	4	4	4
Operating segments \| Exemplar
Segment Reporting Information [Line Items]
Total revenues	$ 717,000	$ 1,767,000	$ 1,782,000	$ 3,618,000

- Definition

Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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Amount of revenue recognized from goods sold, services rendered, insurance premiums, or other activities that constitute an earning process. Includes, but is not limited to, investment and interest income before deduction of interest expense when recognized as a component of revenue, and sales and trading gain (loss).

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-Subparagraph (b)
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+ Details

Organization	6 Months Ended
Organization	Jun. 30, 2024
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Organization	Organization Precigen, Inc. ("Precigen"), a Virginia corporation, is a dedicated discovery and clinical-stage biopharmaceutical company advancing the next generation of gene and cell therapies with the overall goal of improving outcomes for patients with significant unmet medical needs. Precigen is leveraging its proprietary technology platforms to develop product candidates designed to target urgent and intractable diseases in its core therapeutic areas of immuno-oncology, autoimmune disorders, and infectious diseases. Precigen’s primary operations are located in the State of Maryland. Precigen also has two wholly owned operating subsidiaries: Precigen ActoBio, Inc. ("ActoBio"), and Exemplar Genetics, LLC, doing business as Precigen Exemplar ("Exemplar"). Precigen and its consolidated subsidiaries are hereinafter referred to as the "Company." ActoBio utilizes a proprietary class of microbe-based biopharmaceuticals that enable expression and local delivery of disease-modifying therapeutics, with its primary operations located in Ghent, Belgium. As part of a continuing effort to strategically prioritize the application of resources to particular development efforts, during the second quarter of 2024, the Company initiated a shutdown of ActoBio's operations. This included the commencement of terminating leases and employees, and the disposition of certain of its assets and obligations with a focus on the preservation of ActoBio's intellectual property. See Notes 6 and 7 for further discussion related to non-cash impairment charges recorded in relation to these activities. In addition to the impairment charges described in Notes 6 and 7, the Company also recorded a charge related to employee severance and termination benefits of $2,100, of which $1,700 is included in research and development expenses and $400 is included in selling, general and administrative expenses included in the accompanying condensed consolidated statement of operations for the three and six months ended June 30, 2024. No payments had been made for these employee termination benefits through June 30, 2024. In addition to the actions taken at ActoBio noted above, in August, 2024 the Company also began undertaking a strategic prioritization of its clinical portfolio and streamlining of its resources, including a reduction of over 20% of its workforce, to focus on potential commercialization of the PRGN-2012 AdenoVerse® gene therapy for the treatment of recurrent respiratory papillomatosis (RRP). These strategic changes are designed to reduce required resources for non-priority programs and enable the Company to focus on pre-commercialization efforts on PRGN-2012, including supporting submission of a rolling biologics license application (BLA) under an accelerated approval pathway anticipated in the second half of 2024, conducting a confirmatory clinical trial, and manufacturing commercial product. Additionally, the Company will continue acceleration of commercial readiness efforts for a potential launch in 2025. These actions will result in the Company recording severance charges in the third quarter of 2024 related to the reduction in its workforce of approximately $900. Exemplar is committed to enabling the study of life-threatening human diseases through the development of Yucatan MiniSwine preclinical research models and services. Exemplar’s primary operations are located in the State of Iowa.

Commitments and Contingencies	6 Months Ended
Commitments and Contingencies	Jun. 30, 2024
Commitments and Contingencies Disclosure [Abstract]
Commitments and Contingencies	Commitments and Contingencies Contingencies In October 2020, several shareholder class action lawsuits were filed in the United States District Court for the Northern District of California on behalf of certain purchasers of the Company's common stock. The complaints name as defendants the Company and certain of its current and former officers. The plaintiffs' claims challenged disclosures about the MBP program from May 10, 2017 to March 1, 2019. In March 2021, the Court granted an order consolidating the claims and, in April 2021, appointed a lead plaintiff and lead counsel in the case, captioned In re Precigen Securities Litigation, Case No. 5:20-cv-06936-BLF (N.D. Cal.). On May 18, 2021, the lead plaintiff filed an Amended Class Action Complaint. On August 2, 2021, the defendants moved to dismiss the Amended Class Action Complaint. On September 27, 2021, the lead plaintiff filed a Second Amended Class Action Complaint in lieu of a response to the defendants’ motion to dismiss. On November 3, 2021, the defendants moved to dismiss the Second Amended Class Action Complaint and on May 31, 2022, the Court granted the defendants’ motion to dismiss the Second Amended Class Action Complaint with leave to amend. On August 1, 2022, the lead plaintiff filed a Third Amended Class Action Complaint. On August 2, 2022, the Court granted the parties' request to conduct a private mediation session to explore potential resolution of the action. On November 17, 2022, at the conclusion of the mediation session, the parties executed a memorandum of understanding that agreed in principle to resolve the claims asserted in the securities class action. The settlement provides for a payment to the plaintiff class of $13,000. As a result, the shareholder class action lawsuit was resolved. On November 6, 2023, the Court granted final approval of the settlement, dismissed the litigation with prejudice, and entered final judgment. As a result, the Company had no amounts recorded in settlement and indemnification accruals or an insurance receivable asset on the consolidated balance sheet as of June 30, 2024 and December 31, 2023, respectively. In December 2020, a derivative shareholder action, captioned Edward D. Wright, derivatively on behalf of Precigen, Inc. F/K/A Intrexon Corp. v. Alvarez et al, was filed in the Circuit Court for Fairfax County in Virginia on behalf of Precigen, Inc. asserting similar claims under state law against Precigen's current directors and certain officers. The plaintiff seeks damages, forfeiture of benefits received by defendants, and an award of reasonable attorneys' fees and costs. The case was stayed by an order entered on June 14, 2021. On September 24, 2021, an individual shareholder filed a lawsuit in the Circuit Court for Henrico County styled Kent v. Precigen, Inc., Case CL21-6349. The Kent action demands inspection of certain books and records of the Company pursuant to Virginia statutory and common law. On April 1, 2022, the Court denied the demurrer and referred the matter to a hearing on the merits. The Company intends to defend the lawsuits vigorously; however, there can be no assurances regarding the ultimate outcome of these lawsuits. In the course of its business, the Company is involved in litigation or legal matters, including governmental investigations. Such matters are subject to many uncertainties and outcomes are not predictable with assurance. The Company accrues liabilities for such matters when it is probable that future expenditures will be made and such expenditures can be reasonably estimated. As of June 30, 2024, the Company does not believe that any such matters, individually or in the aggregate, will have a material adverse effect on the Company's business, financial condition, results of operations, or cash flows. Trans Ova As part of the Company's strategic shift to becoming a healthcare company, in August 2022, the Company completed the sale of 100% of the issued and outstanding membership interests in its wholly-owned subsidiary, Trans Ova, to Spring Bidco LLC (the “Buyer”), a Delaware limited liability company for $170,000 and up to $10,000 in cash earn-out payments contingent upon the performance of Trans Ova in each of 2022 and 2023, consisting of $5,000 for each year (the “Transaction”). In February 2023, the Buyer notified the Company that Trans Ova did not meet the financial measures required in 2022 in order to require the first $5,000 earn-out payment. In April 2024, the Buyer notified the Company that Trans Ova did not meet the financial measures required in 2023 in order to require the second $5,000 earn-out payment. The Company has disputed certain items reflected in the 2023 financial measures presented by the Buyer in the aforementioned notification. In connection with the Transaction, the Company is required to indemnify the Buyer for certain expenses incurred post close (related to covenants and certain additional specified liabilities including certain patent infringement lawsuits), if incurred, in amounts not to exceed $5,750. Such indemnification was recorded as a reduction of the gain on divestiture in the third quarter of 2023. As of June 30, 2024 and December 31, 2023, $3,213 and $5,750 were included in settlement and indemnification accruals on the condensed consolidated balance sheets, respectively, related to this indemnification liability. During the three months ended June 30, 2024, the Company paid an indemnification claim of $1,862 for expenses incurred by the buyer for the period from July 2023 to December 2023. In addition, during the three months ended September 30, 2023, the Company paid $675 for indemnification claims against this liability for the period from the date of sale to June 2023.

Segments - Reconciliation of Net Loss Before Income Taxes (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA for reportable segments	$ (28,057)	$ (17,337)	$ (52,077)	$ (38,559)
Other expenses:
Depreciation and amortization			(3,191)	(3,404)
Gain on disposals of assets			3	40
Stock-based compensation expense	(1,964)	(2,188)	(4,545)	(5,320)
Shares issued as payment for services			528	545
Consolidated loss before income taxes	(60,481)	(20,384)	(84,248)	(43,173)
Operating segments
Segment Reporting Information [Line Items]
Remove cash paid for capital expenditures, net of proceeds from sale of assets	2,326	101	6,674	255
Interest income	319	828	927	1,461
Corporate And Reconciling Items
Other expenses:
Interest expense	2	136	4	460
Depreciation and amortization	(1,596)	(1,693)	(3,191)	(3,404)
Gain on disposals of assets	0	40	3	40
Impairment losses	(34,545)	0	(34,545)	0
Stock-based compensation expense	(1,964)	(2,188)	(4,545)	(5,320)
Adjustment related to accrued bonuses paid in equity awards	3,039	0	3,039	3,360
Shares issued as payment for services	0	0	(528)	(545)
Other	(1)	1	(1)	(1)
Reportable Segments
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA for reportable segments	$ (28,057)	$ (17,337)	$ (52,077)	$ (38,559)

Condensed Consolidated Statements of Shareholders' Equity - USD ($) $ in Thousands	Total	Common Stock	Treasury Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2022		208,150,021
Beginning balance at Dec. 31, 2022	$ 126,259	$ 0	$ 0	$ 1,998,314	$ (3,488)	$ (1,868,567)
Treasury stock (in shares) beginning balance at Dec. 31, 2022			0
Increase (Decrease) in Stockholders' Equity
Stock-based compensation expense	5,320			5,320
Shares issued upon vesting of restricted stock units and for exercises of stock options and warrants (in shares)		697,815
Shares issued upon vesting of restricted stock units and for exercises of stock options	0
Shares issued for accrued compensation (in shares)		(2,206,469)
Shares issued for accrued compensation	3,361			3,361
Shares issued as payment for services (in shares)		465,808
Shares issued as payment for services	545			545
Shares issued in public offering, net of issuance costs (in shares)		43,962,640
Shares issued in public offerings, net of issuance costs	72,808			72,808
Net loss	(43,053)					(43,053)
Other comprehensive income (loss)	970				970
Ending balance (in shares) at Jun. 30, 2023		255,482,753
Ending balance at Jun. 30, 2023	166,210	$ 0	$ 0	2,080,348	(2,518)	(1,911,620)
Treasury stock (in shares) ending balance at Jun. 30, 2023			0
Beginning balance (in shares) at Mar. 31, 2023		255,482,753
Beginning balance at Mar. 31, 2023	184,133	$ 0	$ 0	2,078,133	(2,699)	(1,891,301)
Treasury stock (in shares) beginning balance at Mar. 31, 2023			0
Increase (Decrease) in Stockholders' Equity
Stock-based compensation expense	2,188			2,188
Shares issued in public offerings, net of issuance costs	27			27
Net loss	(20,319)					(20,319)
Other comprehensive income (loss)	181				181
Ending balance (in shares) at Jun. 30, 2023		255,482,753
Ending balance at Jun. 30, 2023	$ 166,210	$ 0	$ 0	2,080,348	(2,518)	(1,911,620)
Treasury stock (in shares) ending balance at Jun. 30, 2023			0
Beginning balance (in shares) at Dec. 31, 2023	248,919,096	248,919,096
Beginning balance at Dec. 31, 2023	$ 118,498	$ 0	$ 0	2,084,916	(1,947)	(1,964,471)
Treasury stock (in shares) beginning balance at Dec. 31, 2023			7,479,431
Increase (Decrease) in Stockholders' Equity
Stock-based compensation expense	4,545			4,545
Shares issued upon vesting of restricted stock units and for exercises of stock options and warrants (in shares)		1,197,992	1,197,992
Shares issued upon vesting of restricted stock units and for exercises of stock options	52			52
Shares issued for accrued compensation (in shares)		(2,170,885)	(2,170,885)
Shares issued for accrued compensation	3,039			3,039
Shares issued as payment for services (in shares)		368,178	368,178
Shares issued as payment for services	528			528
Net loss	(82,530)					(82,530)
Other comprehensive income (loss)	$ (962)				(962)
Ending balance (in shares) at Jun. 30, 2024	252,656,151	252,656,151
Ending balance at Jun. 30, 2024	$ 43,170	$ 0	$ 0	2,093,080	(2,909)	(2,047,001)
Treasury stock (in shares) ending balance at Jun. 30, 2024			3,742,376
Beginning balance (in shares) at Mar. 31, 2024		250,248,808
Beginning balance at Mar. 31, 2024	97,019	$ 0	$ 0	2,088,025	(2,797)	(1,988,209)
Treasury stock (in shares) beginning balance at Mar. 31, 2024			6,149,719
Increase (Decrease) in Stockholders' Equity
Stock-based compensation expense	1,964			1,964
Shares issued upon vesting of restricted stock units and for exercises of stock options and warrants (in shares)		236,458	236,458
Shares issued upon vesting of restricted stock units and for exercises of stock options	52			52
Shares issued for accrued compensation (in shares)		(2,170,885)	(2,170,885)
Shares issued for accrued compensation	3,039			3,039
Net loss	(58,792)					(58,792)
Other comprehensive income (loss)	$ (112)				(112)
Ending balance (in shares) at Jun. 30, 2024	252,656,151	252,656,151
Ending balance at Jun. 30, 2024	$ 43,170	$ 0	$ 0	$ 2,093,080	$ (2,909)	$ (2,047,001)
Treasury stock (in shares) ending balance at Jun. 30, 2024			3,742,376

Shareholders' Equity - Components of Accumulated Other Comprehensive Income (Loss) (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Mar. 31, 2024	Dec. 31, 2023	Jun. 30, 2023	Mar. 31, 2023	Dec. 31, 2022
Accumulated Other Comprehensive Income (Loss) [Line Items]
Precigen shareholders' equity	$ 43,170	$ 97,019	$ 118,498	$ 166,210	$ 184,133	$ 126,259
Total accumulated other comprehensive loss
Accumulated Other Comprehensive Income (Loss) [Line Items]
Precigen shareholders' equity	(2,909)	$ (2,797)	(1,947)	$ (2,518)	$ (2,699)	$ (3,488)
Unrealized loss on investments
Accumulated Other Comprehensive Income (Loss) [Line Items]
Precigen shareholders' equity	(16)		(33)
Loss on foreign currency translation adjustments
Accumulated Other Comprehensive Income (Loss) [Line Items]
Precigen shareholders' equity	$ (2,893)		$ (1,914)

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References + Details

- Definition

Amount of equity (deficit) attributable to parent. Excludes temporary equity and equity attributable to noncontrolling interest.

+ References

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+ Details

Collaboration and Licensing Revenue

6 Months Ended

Jun. 30, 2024

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Collaboration and Licensing Revenue

The Company's collaborations and licensing agreements may provide for multiple promises to be satisfied by the Company and typically include a license to the Company's technology platforms, participation in collaboration committees, and performance of certain research and development services. Based on the nature of the promises in the Company's collaboration and licensing agreements, the Company typically combines most of its promises into a single performance obligation because the promises are highly interrelated and not individually distinct. Options to acquire additional services are considered to determine if they constitute material rights. At contract inception, the transaction price is typically the upfront payment received and is allocated to the performance obligations. The Company has determined the transaction price should be recognized as revenue based on its measure of progress under the agreement primarily based on inputs necessary to fulfill the performance obligation.

The Company determines whether collaborations and licensing agreements are individually significant for disclosure based on a number of factors, including total revenue recorded by the Company pursuant to collaboration and licensing agreements, collaborators or licensees with equity method investments, or other qualitative factors. Collaboration and licensing revenues generated from consolidated subsidiaries are eliminated in consolidation.

There was no collaboration and licensing revenue recognized during both the three and six months ended June 30, 2024 and 2023.

Alaunos License Agreement

On April 3, 2023, the Company entered into an amended and restated exclusive license agreement (the “License Agreement”), with Alaunos Therapeutics (“Alaunos”). The License Agreement amended and replaced an Exclusive License Agreement by and between the Company and Alaunos, dated October 5, 2018.

Pursuant to the terms of the License Agreement, the Company granted Alaunos an exclusive, worldwide, royalty-free, sub-licensable license to certain patents and know-how to research, develop and commercialize T-cell receptor products, which are referred to as TCR Products, designed for neoantigens for the treatment of cancer or the treatment and prevention of human papilloma virus, or HPV, to the extent that the primary reason for such treatment or prevention is to prevent cancer, which is referred to as the HPV Field. The Company has also granted Alaunos an exclusive, worldwide, royalty-free, sub-licensable license to certain patents relating to the Sleeping Beauty technology to research, develop and commercialize TCR Products

(other than those designed for neoantigens) for the treatment of cancer and in the HPV Field. The Company also granted Alaunos certain non-exclusive rights to certain patents and know-how to research, develop and commercialize products developed under or arising from a program of research and development focused on NK cells and gamma delta T-cells in the HPV field. Alaunos has the exclusive right to conduct in its sole discretion, and is solely responsible for all aspects of, the research, development and commercialization of the licensed products for the treatment of cancer and is not subject to a diligence obligation with respect to such efforts.

The License Agreement will terminate on a product-by-product and/or country-by-country basis upon the expiration of the last to expire patent claim for each licensed product. In addition, Alaunos may terminate the License Agreement on a country-by-country or program-by-program basis following written notice to the Company, and either party may terminate the License Agreement following notice of a material breach subject to a certain cure period.

Neither Alaunos nor the Company will have any other obligations with respect to the payment of milestones or royalties on products developed in connection with the License Agreement.

Deferred Revenue

Deferred revenue primarily consists of upfront and milestone consideration received for the Company's collaboration and licensing agreements. Revenue is recognized as services are performed. The arrangements classified as long-term are not active while the respective counterparties evaluate the status of the project and its desired future development activities since the Company cannot reasonably estimate the amount of services, if any, to be performed over the next year.

Deferred revenue consisted of the following:


	June 30, 2024		December 31, 2023
Collaboration and licensing agreements	$	1,818	$	1,818
Prepaid product and service revenues	15		15
Other	363		494
Total	$	2,196	$	2,327
Current portion of deferred revenue	$	378	$	509
Long-term portion of deferred revenue	1,818		1,818
Total	$	2,196	$	2,327

Operating Leases - Components of Lease Costs (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Leases [Abstract]
Operating lease costs	$ 609	$ 617	$ 1,218	$ 1,232
Short-term lease costs	22	10	35	30
Variable lease costs	92	86	184	206
Lease costs	$ 723	$ 713	$ 1,437	$ 1,468

Goodwill and Intangible Assets, Net - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023	Dec. 31, 2023
Goodwill and Intangible Assets Disclosure [Abstract]
Goodwill, impaired, accumulated impairment loss	$ 26,503		$ 26,503		$ 24,873
Impairment of intangible assets	32,317
Amortization expense	$ 1,208	$ 1,218	$ 2,423	$ 2,423

Operating Leases - Lease Terms and Discount Rates (Details)	Jun. 30, 2024	Dec. 31, 2023
Leases [Abstract]
Weighted average remaining lease term (years)	4 years 10 months 6 days	5 years 4 months 20 days
Weighted average discount rate	11.40%	11.20%

Fair Value Measurements

6 Months Ended

Jun. 30, 2024

Fair Value Disclosures [Abstract]

Fair Value Measurements

The carrying amount of cash and cash equivalents, receivables, accounts payable, accrued compensation and benefits, and other accrued liabilities approximate fair value due to the short maturity of these instruments.

Assets

The following table presents the placement in the fair value hierarchy of financial assets that are measured at fair value on a recurring basis as of June 30, 2024:


	Quoted Prices in Active Markets (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)		June 30, 2024
Assets
U.S. government debt securities	$	—	$	8,343	$	—	$	8,343

Certificates of deposit	—		1,848		—		1,848

Total	$	—	$	10,191	$	—	$	10,191

The following table presents the placement in the fair value hierarchy of financial assets that are measured at fair value on a recurring basis as of December 31, 2023:


	Quoted Prices in Active Markets (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)		December 31, 2023
Assets
U.S. government debt securities	$	—	$	51,671	$	—	$	51,671
Certificates of deposit	—		3,361		—		3,361
Corporate bonds	—		245		—		245
Total	$	—	$	55,277	$	—	$	55,277

The method used to estimate the fair value of the Level 2 short-term investments in the tables above is based on professional pricing sources for identical or comparable instruments, rather than direct observations of quoted prices in active markets.

- Definition

The entire disclosure for the fair value of financial instruments (as defined), including financial assets and financial liabilities (collectively, as defined), and the measurements of those instruments as well as disclosures related to the fair value of non-financial assets and liabilities. Such disclosures about the financial instruments, assets, and liabilities would include: (1) the fair value of the required items together with their carrying amounts (as appropriate); (2) for items for which it is not practicable to estimate fair value, disclosure would include: (a) information pertinent to estimating fair value (including, carrying amount, effective interest rate, and maturity, and (b) the reasons why it is not practicable to estimate fair value; (3) significant concentrations of credit risk including: (a) information about the activity, region, or economic characteristics identifying a concentration, (b) the maximum amount of loss the entity is exposed to based on the gross fair value of the related item, (c) policy for requiring collateral or other security and information as to accessing such collateral or security, and (d) the nature and brief description of such collateral or security; (4) quantitative information about market risks and how such risks are managed; (5) for items measured on both a recurring and nonrecurring basis information regarding the inputs used to develop the fair value measurement; and (6) for items presented in the financial statement for which fair value measurement is elected: (a) information necessary to understand the reasons for the election, (b) discussion of the effect of fair value changes on earnings, (c) a description of [similar groups] items for which the election is made and the relation thereof to the balance sheet, the aggregate carrying value of items included in the balance sheet that are not eligible for the election; (7) all other required (as defined) and desired information.

+ References

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+ Details

Cover Page - shares	6 Months Ended
Cover Page - shares	Jun. 30, 2024	Jul. 31, 2024
Cover [Abstract]
Document Type	10-Q
Document Quarterly Report	true
Document Period End Date	Jun. 30, 2024
Document Transition Report	false
Entity File Number	001-36042
Entity Registrant Name	PRECIGEN, INC.
Entity Incorporation, State or Country Code	VA
Entity Tax Identification Number	26-0084895
Entity Address, Address Line One	20374 Seneca Meadows Parkway
Entity Address, City or Town	Germantown,
Entity Address, State or Province	MD
Entity Address, Postal Zip Code	20876
City Area Code	301
Local Phone Number	556-9900
Title of 12(b) Security	Common Stock, no par value
Trading Symbol	PGEN
Security Exchange Name	NASDAQ
Entity Current Reporting Status	Yes
Entity Interactive Data Current	Yes
Entity Filer Category	Non-accelerated Filer
Entity Small Business	true
Entity Emerging Growth Company	false
Entity Shell Company	false
Entity Common Stock, Shares Outstanding		252,763,043
Amendment Flag	false
Document Fiscal Year Focus	2024
Document Fiscal Period Focus	Q2
Entity Central Index Key	0001356090
Current Fiscal Year End Date	--12-31

Property, Plant and Equipment, Net - Schedule of Property, Plant and Equipment (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Property, Plant and Equipment [Abstract]
Land and land improvements	$ 164	$ 164
Buildings and building improvements	2,629	2,629
Furniture and fixtures	379	530
Equipment	16,628	18,576
Leasehold improvements	4,475	4,380
Breeding stock	83	79
Computer hardware and software	3,213	3,459
Construction and other assets in progress	8,109	1,577
Property, plant and equipment, gross	35,680	31,394
Less: Accumulated depreciation and amortization	(22,229)	(24,283)
Property, plant and equipment, net	$ 13,451	$ 7,111

Income Taxes (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
Income Taxes (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Income Tax Disclosure [Abstract]
Income tax benefit	$ 1,689	$ 65	$ 1,718	$ 120

- Definition

Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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+ Details

Condensed Consolidated Statements of Operations (Parenthetical) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Continuing Operations
Related Party Transaction [Line Items]
Total revenues	$ 717	$ 1,767	$ 1,782	$ 3,618

- Definition

+ References

+ Details

Segments - Adjusted EBITDA by Reportable Segment (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA for reportable segments	$ (28,057)	$ (17,337)	$ (52,077)	$ (38,559)
Biopharmaceuticals
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA for reportable segments	(27,574)	(17,254)	(51,394)	(38,597)
Exemplar
Segment Reporting Information [Line Items]
Segment Adjusted EBITDA for reportable segments	$ (483)	$ (83)	$ (683)	$ 38

Summary of Significant Accounting Policies (Policies)

6 Months Ended

Jun. 30, 2024

Accounting Policies [Abstract]

Basis of Presentation

The accompanying condensed consolidated financial statements are unaudited and have been prepared in accordance with accounting principles generally accepted in the United States of America ("U.S. GAAP"). Certain information and footnote disclosures normally included in the Company's annual financial statements have been condensed or omitted. These interim condensed consolidated financial statements, in the opinion of management, reflect all normal recurring adjustments necessary for fair statement of the Company's financial position as of June 30, 2024 and results of operations and cash flows for the interim periods ended June 30, 2024 and 2023. The year-end condensed consolidated balance sheet data was derived from the Company's audited financial statements but does not include all disclosures required by U.S. GAAP. These interim financial results are not necessarily indicative of the results to be expected for the year ending December 31, 2024, or for any other future annual or interim period. The accompanying interim unaudited condensed consolidated financial statements should be read in conjunction with the audited consolidated financial statements and related notes thereto included in the Company's Annual Report on Form 10-K for the year ended December 31, 2023.

Consolidation

The accompanying condensed consolidated financial statements reflect the operations of Precigen and its majority-owned subsidiaries. All intercompany accounts and transactions have been eliminated.

Research and Development

The Company considers that regulatory requirements inherent in the research and development of new products preclude it from capitalizing such costs. Research and development expenses include salaries and related costs of research and development personnel, including stock-based compensation expense, costs to acquire technology rights, contract research organizations and consultants, facilities, materials and supplies associated with research and development projects as well as various laboratory studies. Costs incurred in conjunction with collaboration and licensing arrangements are included in research and development. Indirect research and development costs include depreciation, amortization, and other indirect overhead expenses.

Cash and Cash Equivalents

All highly liquid investments with an original maturity of three months or less at the date of purchase are considered to be cash equivalents. Cash balances at a limited number of banks may periodically exceed insurable amounts. The Company believes that it mitigates its risk by investing in or through major financial institutions. Recoverability of investments is dependent upon the performance of the issuer.

Short-term Investments

As of June 30, 2024 and December 31, 2023 short-term investments include United States government debt and agency securities and certificates of deposit. The Company determines the appropriate classification as short-term or long-term at the time of purchase based on original maturities and management's reasonable expectation of sales and redemption. The Company reevaluates such classification at each balance sheet date.

Fair Value of Financial Instruments

Fair value is the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants at the measurement date. As such, fair value is a market-based measurement that should be determined based on assumptions that market participants would use in pricing an asset and liability. As a basis for considering such assumptions, the Company uses a three-tier fair value hierarchy that prioritizes the inputs used in its fair value measurements. The hierarchy gives the highest priority to unadjusted quoted prices in active markets for identical assets or liabilities (Level 1 measurements) and the lowest priority to unobservable inputs (Level 3 measurements). The three levels of the fair value hierarchy are as follows:


Level 1:			Quoted prices in active markets for identical assets and liabilities;

Level 2:			Other than quoted prices included in Level 1 inputs that are observable for the asset or liability, either directly or indirectly; and

Level 3:			Unobservable inputs for the asset or liability used to measure fair value to the extent that observable inputs are not available.

Net Loss Per Share

Net Loss per Share

Basic net loss per share is calculated by dividing net loss attributable to common shareholders by the weighted average shares outstanding during the period, without consideration of common stock equivalents. Diluted net loss per share is calculated by adjusting weighted average shares outstanding for the dilutive effect of common stock equivalents outstanding for the period, using the treasury-stock method and the if-converted method. For purposes of the diluted net loss per share calculation, shares to be issued pursuant to stock options and restricted stock units ("RSUs") are considered to be common stock equivalents but are excluded from the calculation of diluted net loss per share because their effect would be anti-dilutive as described in the next paragraph. Therefore, basic and diluted net loss per share were the same for all periods presented. See Note 10 for further discussion of the Company's Share Lending Agreement, which was terminated on October 1, 2023.

Segment Information

The Company's chief operating decision maker ("CODM") regularly reviews disaggregated financial information for various operating segments. The financial information regularly reviewed by the CODM consists of (i) Biopharmaceuticals and (ii) Exemplar, each an operating segment that was also determined to be a reportable segment. The Biopharmaceuticals reportable segment is primarily comprised of the Company's legal entities of Precigen and ActoBio. See Note 1 for a description of Precigen, ActoBio and Exemplar.

Use of Estimates

The preparation of financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, the disclosure of contingent assets and liabilities at the date of the financial statements, and the reported amounts of revenues and expenses during the reporting periods. Actual results could differ from those estimates.

Recently Issued Adopted Pronouncements Not Yet Adopted

Recently Issued Accounting Pronouncements Not Yet Adopted

In November 2023, the FASB issued ASU 2023-07, Segment Reporting—Improvements to Reportable Segment Disclosures. According to ASU 2023-07, public entities are required to disclose its significant segment expense categories and amounts for each reportable segment. A significant segment expense is an expense that is significant to the segment, regularly provided to or easily computed from information regularly provided to the chief operating decision maker and included in the reported measure of segment profit or loss. This updated standard is effective for public entities for fiscal years beginning after December 15, 2023, and interim periods in fiscal years beginning after December 15, 2024. We do not believe the adoption of ASU 2023-07 will have a material impact on our consolidated financial statements and disclosures.

There are no other new accounting standards which have not yet been adopted that are expected to have a significant impact on our financial statements and related disclosures.

Shareholders' Equity

6 Months Ended

Jun. 30, 2024

Equity [Abstract]

Shareholders' Equity

Issuances of Precigen Common Stock

In January 2023, the Company closed a public offering of 43,962,640 shares of its common stock, resulting in net proceeds of $72,808, after deducting underwriting discounts, fees, and other offering expenses. Of the 43,962,640 shares, 11,517,712 shares were purchased by related parties and their affiliates, including the Company's Chief Executive Officer, its Chairman of the Board of Directors and his affiliates, and certain other of the Company's officers.

The Company completed the offering of shares of common stock, utilizing a number of underwriters, with J.P. Morgan Securities LLC acting as representative of the underwriters. The services provided by JP Morgan Securities LLC were in the ordinary course of their role as lead underwriter, for which they received customary fees and commissions.

In August 2024, the Company closed a public offering of 39,878,939 shares of its common stock, resulting in net proceeds to the Company of approximately $31,363, after deducting underwriting discounts, fees, and an estimate of other offering expenses. This included the sale of 4,584,821 shares of the Company’s common stock pursuant to the underwriter’s exercise of

its option to purchase an additional 5,294,117 shares until September 6, 2024. Of the 39,878,939 shares, 23,588,234 shares were purchased by related parties and their affiliates, including the Company's Chairman of the Board of Directors and his affiliates, and one of the Company's executive officers.

Share Lending Agreement

Concurrently with the offering of the Convertible Notes, Precigen entered into a share lending agreement (the "Share Lending Agreement") with J.P. Morgan Securities LLC (the "Share Borrower") pursuant to which Precigen loaned and delivered 7,479,431 shares of its common stock (the "Borrowed Shares") to the Share Borrower. The Share Lending Agreement terminated on October 1, 2023, and the Borrowed Shares were returned to Precigen on October 5, 2023.

The Share Lending Agreement was entered into at fair value and met the requirements for equity classification. Therefore, the value is netted against the issuance of the Borrowed Shares in additional paid-in capital. Additionally, the Borrowed Shares are not included in the denominator for loss per share attributable to Precigen shareholders.

Components of Accumulated Other Comprehensive Loss

The components of accumulated other comprehensive loss are as follows:


	June 30, 2024		December 31, 2023
Unrealized loss on investments	$	(16)	$	(33)
Loss on foreign currency translation adjustments	(2,893)		(1,914)
Total accumulated other comprehensive loss	$	(2,909)	$	(1,947)

- Definition

The entire disclosure for equity.

+ References

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+ Details

Fair Value Measurements (Tables)

6 Months Ended

Jun. 30, 2024

Fair Value Disclosures [Abstract]

Summary of Placement in the Fair Value Hierarchy of Financial Assets that are Measured at Fair Value on a Recurring Basis

The following table presents the placement in the fair value hierarchy of financial assets that are measured at fair value on a recurring basis as of June 30, 2024:


	Quoted Prices in Active Markets (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)		June 30, 2024
Assets
U.S. government debt securities	$	—	$	8,343	$	—	$	8,343

Certificates of deposit	—		1,848		—		1,848

Total	$	—	$	10,191	$	—	$	10,191

The following table presents the placement in the fair value hierarchy of financial assets that are measured at fair value on a recurring basis as of December 31, 2023:


	Quoted Prices in Active Markets (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)		December 31, 2023
Assets
U.S. government debt securities	$	—	$	51,671	$	—	$	51,671
Certificates of deposit	—		3,361		—		3,361
Corporate bonds	—		245		—		245
Total	$	—	$	55,277	$	—	$	55,277

Summary of Significant Accounting Policies (Tables)

6 Months Ended

Jun. 30, 2024

Accounting Policies [Abstract]

Schedule of Antidilutive Securities Excluded from Computation of Net Loss per Share

The following potentially dilutive securities as of June 30, 2024 and 2023, have been excluded from the above computations of diluted weighted average shares outstanding for the three and six months then ended as they would have been anti-dilutive:


	June 30,
	2024	2023

Options	27,403,769	22,325,095
Restricted stock units	786,709	1,877,308

Total	28,190,478	24,202,403

Organization (Details) $ in Thousands	3 Months Ended		6 Months Ended
Organization (Details) $ in Thousands	Sep. 30, 2024 USD ($)	Jun. 30, 2024 USD ($) subsidiary	Jun. 30, 2024 USD ($) subsidiary	Aug. 14, 2024
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Number of wholly owned operating subsidiaries \| subsidiary		2	2
Impairment of property, plant, and equipment		$ 110	$ 110
Forecast
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Severance charges	$ 900
Subsequent Event
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Workforce focus on potential commercialization, percentage				0.20
Employee Severance
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Impairment of property, plant, and equipment		2,100	2,100
Research and development
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Impairment of property, plant, and equipment		1,700	1,700
Selling, general and administrative
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Impairment of property, plant, and equipment		$ 400	$ 400

Summary of Significant Accounting Policies - Research and Development - Additional Information (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Accounting Policies [Abstract]
Research and development commitments not yet incurred	$ 16,895	$ 17,800

Goodwill and Intangible Assets, Net (Tables)

6 Months Ended

Jun. 30, 2024

Goodwill and Intangible Assets Disclosure [Abstract]

Schedule of Changes in Carrying Amount of Goodwill

The changes in the carrying amount of goodwill for the six months ended June 30, 2024 were as follows:


Balance at December 31, 2023	$	26,612
Impairment	(1,630)
Foreign currency translation adjustments	(64)
Balance at June 30, 2024	$	24,918

Schedule of Intangible Assets

Intangible assets consist of the following as of June 30, 2024:


	Gross Carrying Amount		Accumulated Amortization		Net
Patents, developed technologies and know-how	$	15,912	$	(10,821)	$	5,091

Intangible assets consist of the following as of December 31, 2023:


	Gross Carrying Amount		Accumulated Amortization		Net
Patents, developed technologies and know-how	$	82,501	$	(41,800)	$	40,701

- Definition

Tabular disclosure of goodwill by reportable segment and in total which includes a rollforward schedule.

+ References

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-Topic 350
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-Name Accounting Standards Codification
-Section 55
-Paragraph 24
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-URI https://asc.fasb.org/1943274/2147482548/350-20-55-24

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+ Details

Goodwill and Intangible Assets, Net

6 Months Ended

Jun. 30, 2024

Goodwill and Intangible Assets Disclosure [Abstract]

Goodwill and Intangible Assets, Net

The changes in the carrying amount of goodwill for the six months ended June 30, 2024 were as follows:


Balance at December 31, 2023	$	26,612
Impairment	(1,630)
Foreign currency translation adjustments	(64)
Balance at June 30, 2024	$	24,918

The Company had $26,503 and $24,873 of cumulative impairment losses as of June 30, 2024 and December 31, 2023, respectively.

During the three months ended June 30, 2024, in connection with the suspension of ActoBio's operations, as discussed in Note 1, the Company determined the fair value of the ActoBio reporting unit was less than its carrying amount. As a result, the Company recorded a goodwill impairment charge of $1,630, which represented the full amount of goodwill associated with the ActoBio reporting unit.

Intangible assets consist of the following as of June 30, 2024:


	Gross Carrying Amount		Accumulated Amortization		Net
Patents, developed technologies and know-how	$	15,912	$	(10,821)	$	5,091

Intangible assets consist of the following as of December 31, 2023:


	Gross Carrying Amount		Accumulated Amortization		Net
Patents, developed technologies and know-how	$	82,501	$	(41,800)	$	40,701

During the three months ended June 30, 2024, in connection with the suspension of ActoBio's operations, the Company determined the fair value of the certain developed technologies that the Company ceased using was less than its carrying amount. As a result, the Company recorded an impairment charge of $32,317, which is included in impairment of other noncurrent assets in the accompanying condensed consolidated statements of operations.

Amortization expenses were $1,208 and $1,218 for the three months ended June 30, 2024 and 2023, respectively, and $2,423 for the six months ended June 30, 2024 and 2023

Share-Based Payments - Schedule of Stock-Based Compensation Costs (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Stock-based compensation costs	$ 1,964	$ 2,188	$ 4,545	$ 5,320
Cost of products and services
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Stock-based compensation costs	(5)	17	12	35
Research and development
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Stock-based compensation costs	920	582	1,454	1,087
Selling, general and administrative
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Stock-based compensation costs	$ 1,049	$ 1,589	$ 3,079	$ 4,198

Segments

6 Months Ended

Jun. 30, 2024

Segment Reporting [Abstract]

Segments

The Company's CODM assesses the operating performance of and allocates resources for several operating segments using Segment Adjusted EBITDA. Management believes this financial metric is a key indicator of operating results since it excludes noncash revenues and expenses that are not reflective of the underlying business performance of an individual enterprise. The Company defines Segment Adjusted EBITDA as net income (loss) before (i) interest expense and interest income, (ii) income tax expense or benefit, (iii) depreciation and amortization, (iv) stock-based compensation expense, (v) loss on settlement agreements where noncash consideration is paid, (vi) adjustments for accrued bonuses paid in equity awards, (vii) gain or loss on disposals of assets, (viii) loss on impairment of goodwill and other noncurrent assets, (ix) equity in net income loss of affiliates, and (x) recognition of previously deferred revenue associated with upfront and milestone payments as well as cash outflows from capital expenditures and investments in affiliates, but includes proceeds from the sale of assets in the period sold. Segment Adjusted EBITDA excludes the gain or loss on disposals of assets and include proceeds from the sale of assets in the period sold.

Because the Company uses Segment Adjusted EBITDA as its primary measure of segment performance, it has included this measure in its discussion of segment operating results. The Company has also disclosed revenues from external customers and intersegment revenues for each reportable segment. The CODM does not use total assets by segment to evaluate segment performance or allocate resources, and accordingly, these amounts are not required to be disclosed.

For the three and six months ended June 30, 2024, the Company's reportable segments were (i) Biopharmaceuticals and (ii) Exemplar. These identified reportable segments met the quantitative thresholds to be reported separately for the six months ended June 30, 2024. See Note 1 for a description of Biopharmaceuticals and Exemplar.

Segment Adjusted EBITDA by reportable segment was as follows:


	Three Months Ended June 30,				Six Months Ended June 30,
	2024		2023		2024		2023
Biopharmaceuticals	$	(27,574)	$	(17,254)	$	(51,394)	$	(38,597)
Exemplar	(483)		(83)		(683)		38

Segment Adjusted EBITDA for reportable segments	$	(28,057)	$	(17,337)	$	(52,077)	$	(38,559)

The table below reconciles Segment Adjusted EBITDA for reportable segments to consolidated net loss before income taxes:


	Three Months Ended June 30,				Six Months Ended June 30,
	2024		2023		2024		2023
Segment Adjusted EBITDA for reportable segments	$	(28,057)	$	(17,337)	$	(52,077)	$	(38,559)

Remove cash paid for capital expenditures, net of proceeds from sale of assets	2,326		101		6,674		255
Interest Income	319		828		927		1,461

Other expenses:
Interest expense	(2)		(136)		(4)		(460)
Depreciation and amortization	(1,596)		(1,693)		(3,191)		(3,404)
Gain on disposals of assets	—		40		3		40
Impairment losses	(34,545)		—		(34,545)		—

Stock-based compensation expense	(1,964)		(2,188)		(4,545)		(5,320)
Adjustment related to accrued bonuses paid in equity awards	3,039		—		3,039		3,360


Shares issue for payment of services	—		—		(528)		(545)
Other	(1)		1		(1)		(1)


Consolidated loss before income taxes	$	(60,481)	$	(20,384)	$	(84,248)	$	(43,173)

Revenues from external customers in the Exemplar segment consisted of $717 and $1,767 for the three months ended June 30, 2024 and 2023, respectively, and $1,782 and $3,618 for the six months ended June 30, 2024 and 2023, respectively.

Total segment revenues from reportable segments equal total consolidated revenues on the condensed consolidated statements of operations.

For the three months ended June 30, 2024 and 2023, 74.8% and 73.3%, respectively, of total consolidated revenue was attributable to four customers in 2024 and four customer in 2023 in the Exemplar segment. For the six months ended June 30, 2024 and 2023 65.5% and 78.0%, respectively, of total consolidated revenue was attributed to four customers in 2024 and four in 2023, in the Exemplar segment.

As of June 30, 2024 and December 31, 2023, the Company had $0 and $1,958, respectively, of long-lived assets in foreign countries. There were no revenues derived in foreign countries for any periods presented.

- Definition

The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments.

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+ Details

Short-term Investments - Additional Information (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Debt Securities, Available-for-sale [Line Items]
Debt securities, available-for-sale	$ 10,191	$ 55,277
Debt securities, available-for-sale, maturity, allocated and single maturity date, rolling within one year, fair value	10,191
U.S. government debt securities
Debt Securities, Available-for-sale [Line Items]
Debt securities, available-for-sale	$ 8,343	$ 51,671
Debt securities, available-for-sale, term	3 months	3 months
Cash and Cash Equivalents \| U.S. government debt securities
Debt Securities, Available-for-sale [Line Items]
Debt securities, available-for-sale	$ 5,864	$ 1,502

- Definition

Amount of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).

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- Definition

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+ Details

Pay vs Performance Disclosure - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
Pay vs Performance Disclosure - USD ($) $ in Thousands	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Pay vs Performance Disclosure
Net loss	$ (58,792)	$ (20,319)	$ (82,530)	$ (43,053)

- Definition

The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

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+ Details

Share-Based Payments - Additional Information (Details) - shares	May 28, 2024	Jun. 30, 2024	Dec. 31, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Options outstanding (in shares)		27,403,769	22,057,340
Restricted stock units
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
RSUs outstanding (in shares)		786,709	961,534
Precigen Stock Option Plan 2023 Plan and 2013 Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Number of shares authorized for issuance (in shares)		16,418,137
Precigen Stock Option Plan 2013 Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Remaining shares available to grant (in shares)		0
Options outstanding (in shares)		17,633,646
Precigen Stock Option Plan 2013 Plan \| Restricted stock units
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
RSUs outstanding (in shares)		0
Precigen Stock Option Plan 2023 Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Remaining shares available to grant (in shares)		8,042,752
Options outstanding (in shares)		6,004,500
Share-based compensation arrangement by share-based payment award, number of additional shares authorized (in shares)	2,000,000
Precigen Stock Option Plan 2023 Plan \| Restricted stock units
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
RSUs outstanding (in shares)		0
Precigen Stock Option Plan 2019 Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Remaining shares available to grant (in shares)		2,739,963
Options outstanding (in shares)		3,765,623
Number of shares authorized for issuance (in shares)		12,000,000
Precigen Stock Option Plan 2019 Plan \| Restricted stock units
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
RSUs outstanding (in shares)		786,709

Summary of Significant Accounting Policies - Liquidity and Going Concern - Additional Information (Details) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended		6 Months Ended
	Aug. 31, 2024	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023	Dec. 31, 2023
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Net income (loss) attributable to parent		$ (58,792)	$ (20,319)	$ (82,530)	$ (43,053)
Net cash used in operating activities				(37,197)	$ (34,156)
Accumulated deficit		2,047,001		2,047,001		$ 1,964,471
Cash, cash equivalents, and short-term investments		$ 19,536		$ 19,536
Subsequent Event
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Proceeds from issuance initial public offering	$ 31,363

- Definition

The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

+ References

+ Details

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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+ Details

- Definition

Amount of accumulated undistributed earnings (deficit).

+ References + Details

Short-term Investments

6 Months Ended

Jun. 30, 2024

Investments, Debt and Equity Securities [Abstract]

Short-term Investments

The Company's investments are classified as available-for-sale. The following table summarizes the amortized cost, gross unrealized gains and losses, and fair value of available-for-sale investments as of June 30, 2024:


	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses		Aggregate Fair Value
U.S. government debt securities	$	8,359	$	15	$	(31)	$	8,343

Certificates of deposit	1,848		—		—		1,848

Total	$	10,207	$	15	$	(31)	$	10,191

In addition, at June 30, 2024 and December 31, 2023, the Company held a U.S. government debt security valued at $5,864 and $1,502, respectively, which was included in cash and cash equivalents in the condensed consolidated balance sheet as this investment had an original maturity of less than three months when purchased.

The estimated fair value of available-for-sale investments was $10,191 as of June 30, 2024, and these available-for-sale investments all contractually mature within one year.

The following table summarizes the amortized cost, gross unrealized gains and losses, and fair value of available-for-sale investments as of December 31, 2023:


	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses		Aggregate Fair Value
U.S. government debt securities	$	51,704	$	102	$	(135)	$	51,671
Certificates of deposit	3,361		1		(1)		3,361
Corporate bonds	245		—		—		245
Total	$	55,310	$	103	$	(136)	$	55,277

Changes in market interest rates and bond yields cause certain investments to fall below their cost basis, resulting in unrealized losses on investments. The Company does not intend to sell these investments nor is it more likely than not that the Company will be required to sell these investments, prior to maturity or recovery of amortized cost.

Segments (Tables)

6 Months Ended

Jun. 30, 2024

Segment Reporting [Abstract]

Information by Reportable Segment

Segment Adjusted EBITDA by reportable segment was as follows:


	Three Months Ended June 30,				Six Months Ended June 30,
	2024		2023		2024		2023
Biopharmaceuticals	$	(27,574)	$	(17,254)	$	(51,394)	$	(38,597)
Exemplar	(483)		(83)		(683)		38

Segment Adjusted EBITDA for reportable segments	$	(28,057)	$	(17,337)	$	(52,077)	$	(38,559)

Reconciliation of Operating Profit (Loss) from Segments to Consolidated

The table below reconciles Segment Adjusted EBITDA for reportable segments to consolidated net loss before income taxes:


	Three Months Ended June 30,				Six Months Ended June 30,
	2024		2023		2024		2023
Segment Adjusted EBITDA for reportable segments	$	(28,057)	$	(17,337)	$	(52,077)	$	(38,559)

Remove cash paid for capital expenditures, net of proceeds from sale of assets	2,326		101		6,674		255
Interest Income	319		828		927		1,461

Other expenses:
Interest expense	(2)		(136)		(4)		(460)
Depreciation and amortization	(1,596)		(1,693)		(3,191)		(3,404)
Gain on disposals of assets	—		40		3		40
Impairment losses	(34,545)		—		(34,545)		—

Stock-based compensation expense	(1,964)		(2,188)		(4,545)		(5,320)
Adjustment related to accrued bonuses paid in equity awards	3,039		—		3,039		3,360


Shares issue for payment of services	—		—		(528)		(545)
Other	(1)		1		(1)		(1)


Consolidated loss before income taxes	$	(60,481)	$	(20,384)	$	(84,248)	$	(43,173)

Operating Leases (Tables)

6 Months Ended

Jun. 30, 2024

Leases [Abstract]

Components of Lease Costs

The components of lease costs were as follows:


	Three Months Ended June 30,				Six Months Ended June 30,
	2024		2023		2024		2023
Operating lease costs	$	609	$	617	$	1,218	$	1,232
Short-term lease costs	22		10		35		30
Variable lease costs	92		86		184		206
Lease costs	$	723	$	713	$	1,437	$	1,468

Other information related to operating leases in continuing operations was as follows:


	June 30, 2024		December 31, 2023
Weighted average remaining lease term (years)	4.85		5.39
Weighted average discount rate	11.4	%	11.2	%


	Six Months Ended June 30,
	2024		2023
Supplemental disclosure of cash flow information
Cash paid for operating lease liabilities	$	1,144	$	1,022
Operating lease right-of-use assets obtained in exchange for new lease liabilities (includes new leases or modifications of existing leases)	572		373

Maturities of Lease Liabilities

As of June 30, 2024, maturities of lease liabilities, excluding short-term and variable leases, for continuing operations were as follows:


2024	$	1,090
2025	1,611
2026	1,473
2027	1,303
2028	1,260
2029	1,295
Thereafter	552
Total	$	8,584
Present value adjustment	(2,243)
Total	$	6,341
Current portion of operating lease liabilities	$	1,269
Long-term portion of operating lease liabilities	5,072
Total	$	6,341

Property, Plant and Equipment, Net - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Property, Plant and Equipment [Abstract]
Depreciation expense	$ 388	$ 475	$ 768	$ 981
Impairment of property, plant, and equipment	110		110
Operating lease, impairment loss	$ 488		$ 488

Condensed Consolidated Balance Sheets (Parenthetical) - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Shareholders' equity
Accounts receivable allowance for credit losses	$ 0	$ 184
Common stock, no par value (in dollars per share)	$ 0	$ 0
Common stock, shares authorized (in shares)	400,000,000	400,000,000
Common stock, shares issued (in shares)	256,398,527	256,398,527
Common stock, shares outstanding (in shares)	252,656,151	248,919,096

Condensed Consolidated Statements of Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Statement of Comprehensive Income [Abstract]
Net loss	$ (58,792)	$ (20,319)	$ (82,530)	$ (43,053)
Other comprehensive income (loss):
Unrealized gain on investments	16	228	15	491
(Loss) gain on foreign currency translation adjustments	(128)	(47)	(977)	479
Comprehensive loss	$ (58,904)	$ (20,138)	$ (83,492)	$ (42,083)

- Definition

Amount after tax of increase (decrease) in equity from transactions and other events and circumstances from net income and other comprehensive income, attributable to parent entity. Excludes changes in equity resulting from investments by owners and distributions to owners.

+ References + Details

- Definition

The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

+ References

+ Details

- Definition

Amount after tax, before reclassification adjustments of gain (loss) on foreign currency translation adjustments, foreign currency transactions designated and effective as economic hedges of a net investment in a foreign entity and intra-entity foreign currency transactions that are of a long-term-investment nature.

+ References + Details

Summary of Significant Accounting Policies

6 Months Ended

Jun. 30, 2024

Accounting Policies [Abstract]

Summary of Significant Accounting Policies

Basis of Presentation

The accompanying condensed consolidated financial statements reflect the operations of Precigen and its majority-owned subsidiaries. All intercompany accounts and transactions have been eliminated.

Liquidity and Going Concern

During the six months ended June 30, 2024, the Company incurred a net loss of $82,530 and used $37,197 of cash in our operations, and as of June 30, 2024, had an accumulated deficit of $2,047,001. The Company has incurred operating losses since its inception and management expects operating losses and negative cash flows from operations to continue for the foreseeable future and, as a result, the Company will require additional capital to fund its operations and execute its business plan. As of June 30, 2024, the Company had $19,536 in cash, cash equivalents and short-term investments. As discussed in Note 10, the Company raised in August approximately $31,363 in net proceeds in a public offering of its common stock, however, had no committed source of additional funding from either debt or equity financings. The Company is currently exploring a number of potential non-dilutive financings for future liquidity. The Company's current cash and investments position, including the proceeds received from the August 2024 offering, is not sufficient to fund the Company's planned operations through one year after the date the interim financial statements are issued and accordingly, there is substantial doubt about the Company's ability to continue as a going concern. The analysis used to determine the Company's ability to continue as a going concern does not include cash sources outside of the Company's direct control that management expects to be available within the next twelve months.

The Company’s ability to fund its operations on an ongoing basis is dependent upon the successful execution of management’s plans, which include raising additional capital in the near term. This additional capital could be raised through a combination of non-dilutive financings (including debt or royalty monetization financings, collaborations, strategic alliances, monetization of non-core assets, marketing, distribution or licensing arrangements), dilutive financings (including equity and/or debt financings which may include an equity component) and, in the longer term, from revenue related to product sales, to the extent its product candidates receive marketing approval and can be commercialized. There can be no assurance that new financing or other transactions will be available to the Company on commercially acceptable terms, or at all. Also, any collaborations, strategic alliances, monetization of non-core assets or marketing, distribution or licensing arrangement may require the Company to give up some or all of its rights to a product or technology, which in some cases may be at less than the full potential value of such rights. If the Company is unable to obtain additional capital, the Company will assess its capital resources and may be required to delay, reduce the scope of, or eliminate some or all of its operations, which may include research and development and clinical trials. This may have a material adverse effect on the Company’s business, financial condition, results of operations and ability to operate as a going concern.

These interim condensed consolidated financial statements have been prepared on a going concern basis and do not include any adjustments to the amounts and classification of assets and liabilities that may be necessary in the event the Company can no longer continue as a going concern.

Risks and Uncertainties

The Company is subject to a number of risks similar to those of other companies conducting high-risk, early-stage research and development of therapeutic product candidates. Principal among these risks are dependence on key individuals and intellectual property, competition from other products and companies, and the technical risks associated with the successful research, development, and clinical manufacturing of its and its collaborators' therapeutic product candidates.

Research and Development

The Company has research and development arrangements with third parties that include upfront and milestone payments. As of June 30, 2024 and December 31, 2023, the Company had research and development commitments with third parties that had not yet been incurred totaling $16,895 and $17,800, respectively. The commitments are generally cancellable by the Company by providing written notice at least sixty days before the desired termination date.

Cash and Cash Equivalents

Short-term Investments

Fair Value of Financial Instruments


Level 1:			Quoted prices in active markets for identical assets and liabilities;

Level 2:			Other than quoted prices included in Level 1 inputs that are observable for the asset or liability, either directly or indirectly; and

Level 3:			Unobservable inputs for the asset or liability used to measure fair value to the extent that observable inputs are not available.

Net Loss per Share


	June 30,
	2024	2023

Options	27,403,769	22,325,095
Restricted stock units	786,709	1,877,308

Total	28,190,478	24,202,403

Segment Information

Use of Estimates

Recently Issued Accounting Pronouncements Not Yet Adopted

There are no other new accounting standards which have not yet been adopted that are expected to have a significant impact on our financial statements and related disclosures.

Insider Trading Arrangements	3 Months Ended
Insider Trading Arrangements	Jun. 30, 2024
Trading Arrangements, by Individual
Rule 10b5-1 Arrangement Adopted	false
Non-Rule 10b5-1 Arrangement Adopted	false
Rule 10b5-1 Arrangement Terminated	false
Non-Rule 10b5-1 Arrangement Terminated	false

Shareholders' Equity (Tables)

6 Months Ended

Jun. 30, 2024

Equity [Abstract]

Components of Accumulated Other Comprehensive Income

The components of accumulated other comprehensive loss are as follows:


	June 30, 2024		December 31, 2023
Unrealized loss on investments	$	(16)	$	(33)
Loss on foreign currency translation adjustments	(2,893)		(1,914)
Total accumulated other comprehensive loss	$	(2,909)	$	(1,947)

Collaboration and Licensing Revenue (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Deferred Revenue Arrangement [Line Items]
Deferred revenue	$ 2,196	$ 2,327
Current portion of deferred revenue	378	509
Long-term portion of deferred revenue	1,818	1,818
Prepaid product and service revenues
Deferred Revenue Arrangement [Line Items]
Deferred revenue	15	15
Other
Deferred Revenue Arrangement [Line Items]
Deferred revenue	363	494
Collaboration and licensing agreements
Deferred Revenue Arrangement [Line Items]
Deferred revenue	$ 1,818	$ 1,818

Property, Plant and Equipment, Net

6 Months Ended

Jun. 30, 2024

Property, Plant and Equipment [Abstract]

Property, Plant and Equipment, Net

Property, plant and equipment consist of the following:


	June 30, 2024		December 31, 2023
Land and land improvements	$	164	$	164
Buildings and building improvements	2,629		2,629
Furniture and fixtures	379		530
Equipment	16,628		18,576
Leasehold improvements	4,475		4,380
Breeding stock	83		79
Computer hardware and software	3,213		3,459
Construction and other assets in progress	8,109		1,577
	35,680		31,394
Less: Accumulated depreciation and amortization	(22,229)		(24,283)
Property, plant and equipment, net	$	13,451	$	7,111

Depreciation expense was $388 and $475 for the three months ended June 30, 2024 and 2023, respectively, and $768 and $981 for the six months ended June 30, 2024 and 2023, respectively.

As discussed in Note 1, during the three and six months ended June 30, 2024, the Company suspended ActoBio's operations. As a result, the Company reviewed the related property, plant and equipment and right-of-use assets for impairment. Based on the estimated undiscounted cash flows, the Company determined that the related asset values were not fully recoverable and calculated estimated fair values using market participant assumptions. The estimated fair values were lower than the carrying values, and the Company recorded impairment losses of $110 related to property, plant, and equipment and $488 related to the right-of-use assets, which are included in impairment of other noncurrent assets in the accompanying condensed consolidated statements of operations.

Share-Based Payments - Schedule of Stock Option Activity (Details) - $ / shares	6 Months Ended	12 Months Ended
	Jun. 30, 2024	Dec. 31, 2023
Number of Shares
Balances at beginning of period (in shares)	22,057,340
Granted (in shares)	6,852,634
Exercised (in shares)	(36,458)
Forfeited (in shares)	(611,750)
Expired (in shares)	(857,997)
Balances at end of period (in shares)	27,403,769	22,057,340
Exercisable at end of period (in shares)	15,595,522
Weighted Average Exercise Price
Balances at beginning of period (in dollars per share)	$ 6.90
Granted (in dollars per share)	1.41
Exercised (in dollars per share)	1.42
Forfeited (in dollars per share)	1.51
Expired (in dollars per share)	16.23
Balances at period end (in dollars per share)	5.36	$ 6.90
Exercisable, weighted average exercise price, at end of period (in dollars per share)	$ 8.17
Weighted Average Remaining Contractual Term (Years)
Balances, weighted average remaining contractual period	7 years 5 months 19 days	7 years 5 months 19 days
Exercisable at period end, weighted average remaining contractual period	6 years 2 months 12 days

Operating Leases

6 Months Ended

Jun. 30, 2024

Leases [Abstract]

Operating Leases

The Company leases certain facilities and equipment under operating leases. Leases with a lease term of twelve months or less are considered short-term leases and are not recorded on the balance sheet, and expense for these leases is recognized over the term of the lease. All other leases have remaining terms of one to six years, some of which may include options to extend the lease and some of which may include options to terminate the lease within one year. The Company uses judgment to determine whether it is reasonably possible to extend the lease beyond the initial term or terminate before the initial term ends and the length of the possible extension or early termination. The leases are renewable at the option of the Company and do not contain residual value guarantees, covenants, or other restrictions.

The components of lease costs were as follows:


	Three Months Ended June 30,				Six Months Ended June 30,
	2024		2023		2024		2023
Operating lease costs	$	609	$	617	$	1,218	$	1,232
Short-term lease costs	22		10		35		30
Variable lease costs	92		86		184		206
Lease costs	$	723	$	713	$	1,437	$	1,468

As of June 30, 2024, maturities of lease liabilities, excluding short-term and variable leases, for continuing operations were as follows:


2024	$	1,090
2025	1,611
2026	1,473
2027	1,303
2028	1,260
2029	1,295
Thereafter	552
Total	$	8,584
Present value adjustment	(2,243)
Total	$	6,341
Current portion of operating lease liabilities	$	1,269
Long-term portion of operating lease liabilities	5,072
Total	$	6,341

Other information related to operating leases in continuing operations was as follows:


	June 30, 2024		December 31, 2023
Weighted average remaining lease term (years)	4.85		5.39
Weighted average discount rate	11.4	%	11.2	%


	Six Months Ended June 30,
	2024		2023
Supplemental disclosure of cash flow information
Cash paid for operating lease liabilities	$	1,144	$	1,022
Operating lease right-of-use assets obtained in exchange for new lease liabilities (includes new leases or modifications of existing leases)	572		373

Debt (Details) - USD ($)	3 Months Ended	6 Months Ended
Debt (Details) - USD ($)	Jun. 30, 2023	Jun. 30, 2023	Jun. 30, 2024	Dec. 31, 2023	Jul. 31, 2018
3.5% Convertible Notes Due 2023
Line of Credit Facility [Line Items]
Aggregate principal amount					$ 200,000,000
Interest Expense, Debt, Excluding Amortization	$ 108,000	$ 397,000
Interest Expense, Debt, Amortization Of Debt Discount (Premium) And Debt Issuance Costs	$ 26,000	$ 60,000
Revolving Line of Credit \| Exemplar Genetics, LLC
Line of Credit Facility [Line Items]
Line of credit facility, maximum borrowing capacity			$ 5,000,000
Debt instrument, interest rate, stated percentage			8.50%
Line of credit facility, outstanding balance			$ 0	$ 0

Property, Plant and Equipment, Net (Tables)

6 Months Ended

Jun. 30, 2024

Property, Plant and Equipment [Abstract]

Schedule of Property, Plant and Equipment

Property, plant and equipment consist of the following:


	June 30, 2024		December 31, 2023
Land and land improvements	$	164	$	164
Buildings and building improvements	2,629		2,629
Furniture and fixtures	379		530
Equipment	16,628		18,576
Leasehold improvements	4,475		4,380
Breeding stock	83		79
Computer hardware and software	3,213		3,459
Construction and other assets in progress	8,109		1,577
	35,680		31,394
Less: Accumulated depreciation and amortization	(22,229)		(24,283)
Property, plant and equipment, net	$	13,451	$	7,111

Short-term Investments - Summary of Amortized Cost, Gross Unrealized Gains and Losses, and Fair Value of Short-term and Long-term Investments (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Debt Securities, Available-for-sale [Line Items]
Amortized Cost	$ 10,207	$ 55,310
Gross Unrealized Gains	15	103
Gross Unrealized Losses	(31)	(136)
Aggregate Fair Value	10,191	55,277
U.S. government debt securities
Debt Securities, Available-for-sale [Line Items]
Amortized Cost	8,359	51,704
Gross Unrealized Gains	15	102
Gross Unrealized Losses	(31)	(135)
Aggregate Fair Value	8,343	51,671
Certificates of deposit
Debt Securities, Available-for-sale [Line Items]
Amortized Cost	1,848	3,361
Gross Unrealized Gains	0	1
Gross Unrealized Losses	0	(1)
Aggregate Fair Value	$ 1,848	3,361
Corporate bonds
Debt Securities, Available-for-sale [Line Items]
Amortized Cost		245
Gross Unrealized Gains		0
Gross Unrealized Losses		0
Aggregate Fair Value		$ 245

- Definition

Amount of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).

+ References

+ Details

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

+ Details

Label	Element	Value
Restricted Cash, Current	us-gaap_RestrictedCashCurrent	$ 0
Restricted Cash and Cash Equivalents, Noncurrent	us-gaap_RestrictedCashAndCashEquivalentsNoncurrent	$ 270,000

Short-term Investments (Tables)

6 Months Ended

Jun. 30, 2024

Investments, Debt and Equity Securities [Abstract]

Summary of Amortized Cost, Gross Unrealized Gains and Losses, and Fair Value of Short-term and Long-term Investments

The following table summarizes the amortized cost, gross unrealized gains and losses, and fair value of available-for-sale investments as of June 30, 2024:


	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses		Aggregate Fair Value
U.S. government debt securities	$	8,359	$	15	$	(31)	$	8,343

Certificates of deposit	1,848		—		—		1,848

Total	$	10,207	$	15	$	(31)	$	10,191

The following table summarizes the amortized cost, gross unrealized gains and losses, and fair value of available-for-sale investments as of December 31, 2023:


	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses		Aggregate Fair Value
U.S. government debt securities	$	51,704	$	102	$	(135)	$	51,671
Certificates of deposit	3,361		1		(1)		3,361
Corporate bonds	245		—		—		245
Total	$	55,310	$	103	$	(136)	$	55,277

- Definition

Tabular disclosure of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 320
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 9
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481800/320-10-50-9

Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 320
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481800/320-10-50-3

Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 320
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (b)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481800/320-10-50-2

Reference 4: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 320
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (c)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481800/320-10-50-2

Reference 5: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 320
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481800/320-10-50-2

Reference 6: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 320
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (aa)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481800/320-10-50-2

Reference 7: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 320
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (aaa)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481800/320-10-50-2

Reference 8: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 320
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (d)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481800/320-10-50-2

Reference 9: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 320
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481800/320-10-50-3

Reference 10: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 320
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
-Subparagraph (b)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481800/320-10-50-3

Reference 11: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 320
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
-Subparagraph (c)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481800/320-10-50-3

Reference 12: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 320
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
-Subparagraph (d)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481800/320-10-50-3

+ Details

Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023
Cash flows from operating activities
Net loss	$ (82,530)	$ (43,053)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	3,191	3,404
Gain on disposals of assets, net	(3)	(40)
Impairment of goodwill	1,630	0
Impairment of other noncurrent assets	32,915	0
Gain on debt retirement	0	(60)
Amortization of discounts on investments, net	(570)	(721)
Stock-based compensation expense	4,545	5,320
Shares issued as payment for services	528	545
Accretion of debt discount and amortization of deferred financing costs	0	60
Deferred income taxes	(1,718)	(113)
Receivables:
Trade	391	(376)
Other	490	(226)
Prepaid expenses	1,158	2,274
Other assets	55	83
Accounts payable	3,178	(1,536)
Accrued compensation and benefits	1,468	1,804
Other accrued liabilities	(235)	(1,740)
Deferred revenue	(131)	(10)
Lease liabilities	303	229
Settlement and indemnification accruals	(1,862)	0
Net cash used in operating activities	(37,197)	(34,156)
Cash flows from investing activities
Purchases of investments	(51,664)	(128,563)
Sales and maturities of investments	97,335	101,852
Purchases of property, plant and equipment	(6,674)	(255)
Proceeds from sale of assets	3	61
Net cash provided by (used in) investing activities	39,000	(26,905)
Cash flows from financing activities
Proceeds from issuance of shares, net of issuance costs	0	72,808
Payments of long-term debt and convertible notes, including cost to retire of $120 in 2023	0	(43,219)
Proceeds from stock option exercises	52	0
Net cash provided by financing activities	52	29,589
Effect of exchange rate changes on cash, cash equivalents, and restricted cash	(95)	(172)
Net increase (decrease) in cash, cash equivalents, and restricted cash	1,760	(31,644)
Cash, cash equivalents, and restricted cash
Beginning of period	7,848	48,596
End of period	9,608	16,952
Supplemental disclosure of cash flow information
Cash paid during the period for interest	5	1,156
Cash paid during the period for income taxes	4	0
Accrued compensation paid in equity awards	3,039	3,361
Purchases of property and equipment included in accounts payable and other accrued liabilities	1,171	19
Proceeds from sale of assets included in accounts receivable	57	0
Cash, cash equivalents, and restricted cash
Cash and cash equivalents	9,345
Restricted cash included in other receivables	263
Restricted cash included in other assets	0
Cash, cash equivalents, and restricted cash	$ 9,608	$ 16,952

Share-Based Payments (Tables)

6 Months Ended

Jun. 30, 2024

Share-Based Payment Arrangement [Abstract]

Schedule of Stock-Based Compensation Costs

Stock-based compensation costs included in the condensed consolidated statements of operations are presented below:


	Three Months Ended June 30,				Six Months Ended June 30,
	2024		2023		2024		2023
Cost of products and services	$	(5)	$	17	$	12	$	35

Research and development	920		582		1,454		1,087
Selling, general and administrative	1,049		1,589		3,079		4,198

Total	$	1,964	$	2,188	$	4,545	$	5,320

Schedule of Stock Option Activity

Stock option activity was as follows:


	Number of Shares	Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (Years)
Balances at December 31, 2023	22,057,340	$	6.90	7.47
Granted	6,852,634	1.41

Exercised	(36,458)	1.42
Forfeited	(611,750)	1.51
Expired	(857,997)	16.23
Balances at June 30, 2024	27,403,769	5.36		7.47
Exercisable at June 30, 2024	15,595,522	8.17		6.20

Schedule of Restricted Stock Unit Activity

RSU activity was as follows:


	Number of Restricted Stock Units	Weighted Average Grant Date Fair Value		Weighted Average Remaining Contractual Term (Years)
Balances at December 31, 2023	961,534	$	1.17	0.19
Granted	4,464,724	1.42
Vested	(4,639,549)	1.37
Forfeited	—	—
Balances at June 30, 2024	786,709	1.43		0.62

Debt	6 Months Ended
Debt	Jun. 30, 2024
Debt Disclosure [Abstract]
Debt	Debt Lines of Credit Exemplar has a $5,000 revolving line of credit with a bank that matures on November 1, 2024. As of June 30, 2024, the line of credit bore interest at a stated rate of 8.50% per annum. As of June 30, 2024 and December 31, 2023, there was no outstanding balance on the line of credit. Convertible Notes In July 2018, Precigen completed a registered underwritten public offering of $200,000 aggregate principal amount of Convertible Notes and issued the Convertible Notes under an indenture between Precigen and The Bank of New York Mellon Trust Company, N.A., as trustee, as supplemented by the First Supplemental Indenture. The Convertible Notes matured on July 1, 2023, although certain notes were repurchased prior to their maturity beginning in third quarter of 2022. On June 30, 2023, the Company repurchased all remaining outstanding Convertible Notes at par plus accrued interest. The components of interest expense in 2023 related to the Convertible Notes were $108 of cash interest expense and $26 of non-cash interest expense for the three months ended June 30, 2023, and $397 of cash interest expense and $60 of non-cash interest expense for the six months ended June 30, 2023

- Definition

The entire disclosure for information about short-term and long-term debt arrangements, which includes amounts of borrowings under each line of credit, note payable, commercial paper issue, bonds indenture, debenture issue, own-share lending arrangements and any other contractual agreement to repay funds, and about the underlying arrangements, rationale for a classification as long-term, including repayment terms, interest rates, collateral provided, restrictions on use of assets and activities, whether or not in compliance with debt covenants, and other matters important to users of the financial statements, such as the effects of refinancing and noncompliance with debt covenants.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 470
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-Name Accounting Standards Codification
-Section 50
-Paragraph 6
-Subparagraph (b)
-Publisher FASB
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Reference 2: http://www.xbrl.org/2003/role/disclosureRef
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Reference 9: http://www.xbrl.org/2003/role/disclosureRef
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+ Details

Commitments and Contingencies (Details) - USD ($)	3 Months Ended		6 Months Ended
Commitments and Contingencies (Details) - USD ($)	Jun. 30, 2024	Sep. 30, 2023	Jun. 30, 2024	Jun. 30, 2023	Dec. 31, 2023	Aug. 31, 2022
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Insurance settlements receivable	$ 0		$ 0		$ 0
Settlement and indemnification accruals decrease			1,862,000	$ 0
Discontinued Operations, Held-for-sale \| Trans Ova
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Disposal group, including discontinued operation, ownership interest disposed of						100.00%
Consideration						$ 170,000,000
Disposal group, including discontinued operation, earn-out payments, range of outcomes, value high						10,000,000
Disposal group, including discontinued operation, indemnification claim	3,213,000		3,213,000		5,750,000
Disposal group, including discontinued operation, indemnification claim paid	1,862,000
Settlement and indemnification accruals decrease		$ 675,000
Discontinued Operations, Held-for-sale \| Trans Ova \| Maximum
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Disposal group, including discontinued operation, earn-out payments						$ 5,000,000
Disposal group, including discontinued operation, reimbursement limit	5,750,000		5,750,000
Precigen Securities Litigation
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Loss contingency accrual	$ 13,000,000		$ 13,000,000		$ 13,000,000

Operating Leases - Additional Information (Details)	6 Months Ended
Operating Leases - Additional Information (Details)	Jun. 30, 2024
Lessee, Lease, Description [Line Items]
Termination period	1 year
Minimum
Lessee, Lease, Description [Line Items]
Term of contract	1 year
Maximum
Lessee, Lease, Description [Line Items]
Term of contract	6 years

Goodwill and Intangible Assets, Net - Schedule of Changes in Carrying Amount of Goodwill (Details) - USD ($) $ in Thousands	3 Months Ended	6 Months Ended
	Jun. 30, 2024	Jun. 30, 2024	Jun. 30, 2023
Goodwill
Beginning balance		$ 26,612
Impairment	$ (1,630)	(1,630)	$ 0
Foreign currency translation adjustments		(64)
Ending balance	$ 24,918	$ 24,918

- Definition

Amount, after accumulated impairment loss, of asset representing future economic benefit arising from other asset acquired in business combination or from joint venture formation or both, that is not individually identified and separately recognized.

+ References

Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Topic 280
-SubTopic 10
-Name Accounting Standards Codification
-Section 55
-Paragraph 49
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-URI https://asc.fasb.org/1943274/2147478546/942-210-S99-1

+ Details

Summary of Significant Accounting Policies - Cash and Cash Equivalents and Restricted Cash - Additional Information (Details)	6 Months Ended
	Jun. 30, 2024
Accounting Policies [Abstract]
Highly liquid investment maximum maturity period	3 months

Collaboration and Licensing Revenue (Tables)

6 Months Ended

Jun. 30, 2024

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Summary of Deferred Revenue

Deferred revenue consisted of the following:


	June 30, 2024		December 31, 2023
Collaboration and licensing agreements	$	1,818	$	1,818
Prepaid product and service revenues	15		15
Other	363		494
Total	$	2,196	$	2,327
Current portion of deferred revenue	$	378	$	509
Long-term portion of deferred revenue	1,818		1,818
Total	$	2,196	$	2,327

Condensed Consolidated Statements of Operations - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Operating Expenses
Impairment of goodwill	$ 1,630		$ 1,630	$ 0
Impairment of other noncurrent assets			32,915	0
Other Income (Expense), Net
Loss before income taxes	(60,481)	$ (20,384)	(84,248)	(43,173)
Income tax benefit	1,689	65	1,718	120
Net loss	$ (58,792)	$ (20,319)	$ (82,530)	$ (43,053)
Net loss per share
Net loss per share, basic (in dollars per share)	$ (0.23)	$ (0.08)	$ (0.33)	$ (0.18)
Net loss per share, diluted (in dollars per share)	$ (0.23)	$ (0.08)	$ (0.33)	$ (0.18)
Weighted average shares outstanding, basic (in shares)	252,366,533	248,003,322	250,803,790	240,307,403
Weighted average shares outstanding, diluted (in shares)	252,366,533	248,003,322	250,803,790	240,307,403
Continuing Operations
Revenues
Total revenues	$ 717	$ 1,767	$ 1,782	$ 3,618
Operating Expenses
Research and development	15,693	11,874	29,942	24,037
Selling, general and administrative	10,306	9,316	20,457	20,954
Impairment of goodwill	1,630	0	1,630	0
Impairment of other noncurrent assets	32,915	0	32,915	0
Total operating expenses	61,558	22,887	87,033	48,215
Operating loss	(60,841)	(21,120)	(85,251)	(44,597)
Other Income (Expense), Net
Interest expense	(2)	(136)	(4)	(460)
Interest income	319	828	927	1,460
Other income, net	43	44	80	424
Total other income, net	360	736	1,003	1,424
Loss before income taxes	(60,481)	(20,384)	(84,248)	(43,173)
Income tax benefit	1,689	65	1,718	120
Continuing Operations \| Product revenues
Revenues
Total revenues	31	324	169	648
Continuing Operations \| Service revenues
Revenues
Total revenues	673	1,438	1,592	2,965
Operating Expenses
Cost of products and services	1,014	1,697	2,089	3,224
Continuing Operations \| Other revenues
Revenues
Total revenues	$ 13	$ 5	$ 21	$ 5

Fair Value Measurements (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Assets
Total	$ 10,191	$ 55,277
Quoted Prices in Active Markets (Level 1)
Assets
Total	0	0
Significant Other Observable Inputs (Level 2)
Assets
Total	10,191	55,277
Significant Unobservable Inputs (Level 3)
Assets
Total	0	0
U.S. government debt securities
Assets
Total	8,343	51,671
U.S. government debt securities \| Quoted Prices in Active Markets (Level 1)
Assets
Total	0	0
U.S. government debt securities \| Significant Other Observable Inputs (Level 2)
Assets
Total	8,343	51,671
U.S. government debt securities \| Significant Unobservable Inputs (Level 3)
Assets
Total	0	0
Certificates of deposit
Assets
Total	1,848	3,361
Certificates of deposit \| Quoted Prices in Active Markets (Level 1)
Assets
Total	0	0
Certificates of deposit \| Significant Other Observable Inputs (Level 2)
Assets
Total	1,848	3,361
Certificates of deposit \| Significant Unobservable Inputs (Level 3)
Assets
Total	$ 0	0
Corporate bonds
Assets
Total		245
Corporate bonds \| Quoted Prices in Active Markets (Level 1)
Assets
Total		0
Corporate bonds \| Significant Other Observable Inputs (Level 2)
Assets
Total		245
Corporate bonds \| Significant Unobservable Inputs (Level 3)
Assets
Total		$ 0

Operating Leases - Other Information (Details) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023
Supplemental disclosure of cash flow information
Cash paid for operating lease liabilities	$ 1,144	$ 1,022
Operating lease right-of-use assets obtained in exchange for new lease liabilities (includes new leases or modifications of existing leases)	$ 572	$ 373

Shareholders' Equity - Additional Information (Details) - USD ($) $ in Thousands	1 Months Ended			3 Months Ended	6 Months Ended
	Aug. 31, 2024	Jan. 31, 2023	Jul. 31, 2018	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Accumulated Other Comprehensive Income (Loss) [Line Items]
Shares issued (in shares)		43,962,640
Proceeds from issuance of shares, net of issuance costs		$ 72,808			$ 0	$ 72,808
Shares issued during the period, value				$ 27		$ 72,808
Stock Issued During Period, Shares, Other			7,479,431
Subsequent Event
Accumulated Other Comprehensive Income (Loss) [Line Items]
Shares issued (in shares)	39,878,939
Shares issued during the period, value	$ 31,363
Related Parties, Aggregated
Accumulated Other Comprehensive Income (Loss) [Line Items]
Shares issued (in shares)		11,517,712
Related Parties, Aggregated \| Subsequent Event
Accumulated Other Comprehensive Income (Loss) [Line Items]
Shares issued (in shares)	23,588,234

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References + Details

- Definition

Equity impact of the value of new stock issued during the period. Includes shares issued in an initial public offering or a secondary public offering.

+ References + Details

Goodwill and Intangible Assets, Net - Schedule of Intangible Assets (Details) - Patents, developed technologies and know-how - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Finite-Lived Intangible Assets, Net [Abstract]
Gross Carrying Amount	$ 15,912	$ 82,501
Accumulated Amortization	(10,821)	(41,800)
Net	$ 5,091	$ 40,701